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Brian M. Cali


Co-Founder and Vice President of Program Management

Ironwood Pharmaceuticals Total Funding ($634,000,000)

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Brian Cali co‐founded Ironwood in 1998 and has served as Senior Vice President of Preclinical Research and Development (R&D) since 2010. He is focused on helping the R&D organization execute on its strategy to advance an exciting pipeline of new product candidates, building on the science team’s core expertise in gastrointestinal disorders and guanylate cyclase pathways. Prior to this role, Brian oversaw program management, helping to ensure effective leadership for cross‐functional research and development teams, as well as product alliances. Before founding Ironwood, Brian was the Chiron fellow of the Life Sciences Research Foundation at Whitehead Institute for Biomedical Research. He holds a Ph.D. in cellular and molecular biology from the University of Wisconsin–Madison and earned a B.S. in microbiology from Cornell University.